Amjevita/adalimumab-atto Cost, Side effects, Dosage, Uses for multiple inflammatory diseases

Read about Amjevita/adalimumab-atto Cost, Side effects, Dosage, Uses for multiple inflammatory diseases. Amjevita is manufactured by Amgen, Inc., of Thousand Oaks, California.

The U.S. Food and Drug Administration has approved a new biosimilar drug Amjevita that contains adalimumab-atto as an active pharmaceutical ingredient.Amjevita is a biosimilar to previously approved drug Humira manufactured by AbbVie Inc. of North Chicago, Illinois.

   
Amjevita/adalimumab-atto basic mechanism is inhibition or suppression tumor necrosis factor alpha (TNFa) which is main culprit for inflammatory response in inflammatory diseases (auto-immune) like rheumatoid arthritis, psoriatric arthritis, ankylosing spondylitis etc.It was observed during clinical trial that administration of adalimumab and methotrexate (MTX) provide synergistic effect and doubles the therapeutic efficacy of methotrexate. Apart from these indications Amjevita/adalimumab-atto can also be used in a patho-physiological condition where suppression of immune system is required. This drug is administered through subcutaneous route (sc).

Multiple inflammatory diseases is a group of disorders that belongs to malfunctioning of immune system. Most common examples of these diseases are rheumatoid arthritis, ulcerative colitis, crohn's disease, hidradenitis suppurativa, juvenile idiopathic arthritis. All kinds of auto-immune disorders are treated and managed by following combination of therapy like DMARD's, Immunosuppressants, Steroidal drugs, etc.

Amjevita/adalimumab-atto Cost, Side effects, Dosage, Uses for multiple inflammatory diseases

 Amjevita/adalimumab-atto Side effects


Amjevita is a biosimilar of Humira  so, both have almost same kind of indications and side effects. These side effects can be categorized into moderate to severe.

Moderate Side effects 

  • Generalized weakness
  • feeling of numbness
  • Body pain
  • Shortness of breath
  • vision problems
  • skin rashes
  • swelling on body

Severe Side effects

Severe kind of side effects associated with this drugs are increase risk of

  • Infections like respiratory infection, liver and kidney infection.
  • Malignancy  

Amjevita/adalimumab-atto Uses

U.S FDA approved this drug for multiple inflammatory diseases which is a class of auto-immune disorders. Auto-immune disorders are of many types like rheumatoid arthritis, ulcerative colitis, crohn's disease, hidradenitis suppurativa, juvenile idiopathic arthritis. This drug can also be used in combination with other drugs like methotrexate.

Amjevita/adalimumab-atto Dosage

This drug is formulated as pre-filled syringe with potency of 40mg/0.8ml. Standard dosage of amevita/adalimumab  is 40mg after every two weeks. It is administered subcutaneously and dose may be adjusted depending upon the severity of disease and patient condition. During this therapy your health care provider may also prescribe you some other DMARD's like methotrexate to make the treatment more effective.

Amjevita/adalimumab-atto Cost/Price 

According to market survey this drug is currently not available at retail pharmacies because it is recently approved by FDA and is under manufacturing process. Once, it will be available at retail outlets we will let you know about the unit cost of drug and its dosage frequency.

Share this

Related Posts

Previous
Next Post »

Leave a reply