Cinqair/reslizumab Cost, Side effects, Uses for asthma

Read about Cinqair/reslizumab Cost, Side effects, Uses for asthma. Cinqair is made by Teva Pharmaceuticals in Frazer, Pennsylvania.

Asthma is a chronic disease that causes inflammation in the airways of the lungs. During an asthma attack, airways become narrow making it hard to breathe. Severe asthma attacks can lead to asthma-related hospitalizations because these attacks can be serious and even life-threatening.

Cinqair is administered once every four weeks via intravenous infusion by a health care professional in a clinical setting prepared to manage anaphylaxis. Cinqair is a humanized interleukin-5 antagonist monoclonal antibody produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. Cinqair reduces severe asthma attacks by reducing the levels of blood eosinophils, a type of white blood cell that contributes to the development of asthma.

According to the Centers for Disease Control and Prevention, as of 2013, more than 22 million people in the U.S. have asthma, and there are more than 400,000 asthma-related hospitalizations each year.


This drug is presented to FDA in capsule dosage form but it’s potency and dosage frequency is difficult to evaluate until it appears in the market. So, we will update all the parameters of drug once, it gets available in the market.


Cinqair/reslizumab Side effects

Cinqair can cause serious side effects including
  • Allergic (hypersensitivity) reactions
  • Anaphylactic shock
These reactions can be life-threatening.

The most common side effects in clinical trials for Cinqair included anaphylaxis, cancer, and muscle pain.
  • Skin rash (hives)
  • Swelling of your face, lips, mouth, or tongue
  • Symptoms of low blood pressure (fainting, dizziness, light headache, confusion, fast heart beat)
  • Itching
  • Paleness
  • Flushing
  • Nausea or abdominal discomfort
  • Breathing problems

Cinqair/reslizumab Prescribing Information

Cinqair is approved for patients who have a history of severe asthma attacks (exacerbation's) despite receiving their current asthma medicines.

Cinqair/reslizumab Cost/Price

This drug is administered by your healthcare practitioner (HCP), which usually means:
  • It may comes under special items category.
  • You cannot fill this prescription in a regular pharmacy. Your doctor, hospital, or clinic will provide this  medication because of possible complications or other issues.
  • This drug is likely to be covered under your medical benefit if you have insurance.

Cinqair/reslizumab Dosage 

Cinqair is administered by intravenous (IV) infusion according weight of body 3 mg/kg one time in every 4 weeks. This dose frequency and potency may be adjusted by your health care provider depending upon disease condition.

Taltz/ixekizumab Cost, Side effects, Uses for Psoriasis

Read about Taltz/ixekizumab Cost, Side effects, Uses for Psoriasis. Taltz is marketed by Indanapolis, Indiana-based Eli Lilly and Company.

Taltz is administered as an injection. It is intended for patients who are candidates for systemic therapy (treatment using substances that travel through the bloodstream, after being taken by mouth or injected), phototherapy (ultraviolet light treatment) or a combination of both.

Taltz’s active ingredient is an antibody (ixekizumab) that binds to a protein (interleukin (IL)-17A) that causes inflammation. By binding to the protein, ixekizumab is able to inhibit the inflammatory response that plays a role in the development of plaque psoriasis.

Psoriasis is a skin condition that causes patches of skin redness and flaking. Psoriasis is an autoimmune disorder that occurs more commonly in patients with a family history of the disease, and most often begins in people between the ages of 15 and 35. The most common form of psoriasis is plaque psoriasis, in which patients develop thick, red skin with flaky, silver-white scales.

Taltz/ixekizumab Cost, Side effects, Uses for Psoriasis

Taltz/ixekizumab  Side effects

  • Serious allergic reactions and development or worsening of inflammatory bowel disease have been reported with the use of Taltz. Monitor patients closely for these conditions. 
  • The most common side effects include upper respiratory infections, injection site reactions and fungal (tinea) infections.

Taltz/ixekizumab  Prescribing Information

US FDA has approved this medicine to treat adults with moderate-to-severe plaque psoriasis.

Taltz/ixekizumab Dosage

 This drug is formulated as pre-filled single syringe having drug volume 80mg/ml. Dosage frequency of this drug is160mg subcutaneously at first week then 80mg subcutaneously every second week (q2wks). After the administration of 7th dose administer 80mg subcutaneously every fourth week (SC q4wks). 

Taltz/ixekizumab Cost/Price

Single pack that contains 1 syringe of Taltz 80mg/ml costs about 5000$ to 4000$. This price may variate with the passage of time so, make it confirm by visiting your nearby pharmacy before purchasing.

Anthim (obiltoxaximab) Side effects, Cost, Uses, for Anthrax

Read about Anthim (obiltoxaximab) Side effects, Cost, Uses, for Anthrax. Anthim was developed by Elusys Therapeutics, Inc. of Pine Brook, New Jersey, in conjunction with the U.S. Department of Health and Human Services’ Biomedical Advanced Research and Development Authority.

U.S. Food and Drug Administration approved Anthim (obiltoxaximab) injection to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

 Inhalational anthrax is a rare disease that can occur after exposure to infected animals or contaminated animal products, or as a result of an intentional release of anthrax spores. It is caused by breathing in the spores of the bacterium Bacillus anthracis. When inhaled, the anthrax bacteria replicate in the body and produce toxins that can cause massive and irreversible tissue injury and death. Anthrax is a potential bioterrorism threat because the spores are resistant to destruction and can be spread by release in the air.

Anthim is a monoclonal antibody that neutralizes toxins produced by B. anthracis. Anthim was approved under the FDA’s Animal Rule, which allows efficacy findings from adequate and well-controlled animal studies to support FDA approval when it is not feasible or ethical to conduct efficacy trials in humans.


Anthim (obiltoxaximab) Side effects, Cost, Uses, for Anthrax


 Anthim (obiltoxaximab) Side effects

 The safety of Anthim was evaluated in 320 healthy human volunteers. The most frequently reported side effects were
  • Headache
  • Itching (pruritus)
  • Upper respiratory tract infections
  • Cough
  • Nasal congestion
  • Hives
  • Bruising
  • Swelling
  • Pain at the infusion site

 Anthim (obiltoxaximab) Prescribing Information

Anthim (obiltoxaximab) injection is prescribed to treat inhalational anthrax in combination with appropriate antibacterial drugs. Anthim is also prescribed to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

 Anthim (obiltoxaximab) Dosage

This drug is formulated as single-dose vial having 600mg/6mL (100mg/mL) solution of obiltoxaximab/anthim. However, standard dosage frequency of anthim is 16 mg/kg IV for those having weight 40Kg or less. Similarly, for those having weight more than 40Kg dosage frequency should be 24 mg/kg IV.

Anthim (obiltoxaximab) Cost/Price

This drug is administered by your healthcare practitioner (HCP), which usually means:
  • It may comes under special items category.
  • You cannot fill this prescription in a regular pharmacy. Your doctor, hospital, or clinic will provide this  medication because of possible complications or other issues.
  • This drug is likely to be covered under your medical benefit if you have insurance.

Xalkori Cost, Side effects, Uses for lung cancer

Read about Xalkori Cost, Side effects, Uses for lung cancer. Xalkori is marketed by Pfizer, based in New York, New York.

 The U.S. Food and Drug Administration approved Xalkori (crizotinib) to treat people with advanced (metastatic) non-small cell lung cancer (NSCLC) whose tumors have an ROS-1 gene alteration. Xalkori is the first and only FDA approved treatment for patients with ROS-1 positive NSCLC.

 Xalkori is an oral medication that blocks the activity of the ROS-1 protein in tumors that have ROS-1 gene alterations. This effect on ROS-1 may prevent NSCLC from growing and spreading.

 Lung cancer is the leading cause of cancer-related deaths in the United States, with an estimated 221,200 new diagnoses and 158,040 deaths in 2015, according to the National Cancer Institute.  ROS-1 gene alterations, thought to lead to abnormal cells, have been identified in various cancers, including NSCLC. ROS-1 gene alterations are present in approximately 1 percent of patients with NSCLC.

Xalkori Cost, Side effects, Uses for lung cancer

Xalkori Side effects

The most common side effects of Xalkori are
  1. Vision disorders
  2. Nausea, diarrhea
  3. Vomiting, swelling (edema)
  4. Constipation
  5. liver problems (elevated transaminases)
  6. Fatigue, decreased appetite
  7. Upper respiratory infection
  8. Dizziness and numbness
  9. Tingling in the hands or feet (neuropathy). 
  10. Fatal inflammation of the lungs
  11. Abnormal heartbeats and partial
  12.  Complete loss of vision in one or both eyes

 Xalkori Cost and Dosage

Xalkori has 200mg potency and 250mg potency. One pack of Xalkori contains 60 capsules. Cost of 200mg Xalkori pack is £51,027 and 250mg is £51,600 approximately. This price may variate with the passage of time so, make it confirm by visiting your nearby pharmacy before purchasing.

Dosing interruption and/or dose reduction to 200 mg PO q12hr may be required based on safety and tolerability; decrease to 250 mg PO qDay if further reduction is needed.